Consistent with our observation of increased CXCL-1 expression levels, we observed on day 6, a ∼4-fold increase in the accumulation of Ly6G+ cells, as compared to controls, in areas of the liver infiltrated by tumor cells (Figure 2A) and this was not observed in iLID2D mice (Figure 2B). Here, CXCL1 is linked to neoplasm.