These include LIF, induced by TGFβ in GBM initiating cells and supporting their self-renewal and migration ability [22], or other genes working in glucose metabolism, as hexokinase 3 (HK3), or in detoxification of ROS, as glutathione peroxidase 3 (GPX3) [23]. The gene discussed is TGFB1; the disease is glioblastoma.