We focused on exploring the integration of understudied kinases into kinase networks within the context of breast cancer, which has three primary subtypes that include luminal (further sub-divided into luminal A and B subtypes) as well as the majority of HER2+ breast cancers along with triple negative breast cancer (TNBC), that can itself be broken into basal-like and claudin-low subtypes [4]. The gene discussed is ERBB2; the disease is breast cancer.