GSR and neuroblastoma: In SH-SY5Y neuroblastoma cells, the 3′-UTR of NFE2L2 is targeted by miR-153, miR27a, and miR-142-5p, with a consequent decrease in Gclc glutamate-cysteine ligase (GCLC) and glutathione-disulfide reductase (GSR) expression levels [86].