DDHD2 and hyperlipidemia: Risk of breast cancer reoccurrence has been correlated with, overall hyperlipidemia including high serum cholesterol, LDL-cholesterol and triglycerides.26 According to the past study low level of HDL and high level of LDL-cholesterol promotes metastasis & proliferation.27 The increased level of triglycerides may be attributed to the decreased hepatic triglyceride lipase activity.28