GPT and hepatocellular carcinoma: Around 20% to 30% Patient with chronic HCV infection have normal ALT level.3 It is a generally considered that Patients with normal ALT have lesser degree of inflammation & fibrosis and slower progression of disease as compared to cases with higher liver enzymes.4 Majority of the HCV carrier with normal ALT have normal to mild inflammation & fibrosis on liver biopsy while some studies have shown contradictory observations like so called “Healthy HCV Carrier” may have advanced fibrosis or even cirrhosis and Hepatocellular Carcinoma.5