In China there is predominance of MPA while GPA is rare and it is noteworthy that GPA patients from China are mostly p-ANCA / MPO-ANCA positive while in Europe, GPA is mostly c-ANCA / PR3 -ANCA positive.12-14 In northwestern Turkey frequency of AAV was similar to that in southern Europe.15 In our patients GPA was more frequent than MPA and EGPA and c-ANCA / PR3 ANCA associated vasculitis was more common than p-ANCA / MPO-ANCA similar to European patients. This evidence concerns the gene MPO and microscopic polyangiitis.