CAMP and rosacea: A role of LL-37 in the pathogenesis of rosacea could be demonstrated by the application of ivermectin in keratinocytes and 3D skin models which displayed an anti-inflammatory effect by suppressing expression of LL-37 and the protease kallikrein-related peptidase (KLK)5 (Thibaut de Menonville et al., 2017).