For example, PRDX3 is a mitochondrial protein with an antioxidant function which can negatively regulate apoptotic process, protect cells from oxidative stress, and promote cell survival in cancer (37); SEPW1 is a selenoprotein and an antioxidant involved in p53 signaling during cell apoptosis (38); STAT3 is in the STAT protein family, the members of which are key transcription activators involved in many cellular processes such as cell growth and apoptosis (39). Here, SELENOW is linked to cancer.