IL6 and metastatic melanoma: Remarkably, we found that metastatic melanoma patients with normal IL6 serum levels had longer survival after ipilimumab treatment, although IL6 baseline concentration didn’t retain it’s significance when we analyzed its prognostic value for survival in a multivariate analysis that also identified baseline LDH and neutrophil count as prognostic biomarkers [29], while LDH and neutrophil count did.