While the correlation of these motif counts and kataegis measures with drug sensitivity in PAAD is notable, none of the five candidate genes had significantly associated expression with sensitivity to these agents in PAAD cell lines, although, as discussed above, in the NSCLC cell lines, log(IC50) of AKT inhibitor VIII was correlated with REV1 expression (Table 6; ρ = 0.373, padj = 2.51 × 10−5, n = 121, Ntests = 26,610). Here, AKT1 is linked to pancreatic adenocarcinoma.