When compared to the mean APOBEC3A and APOBEC3B gene expression levels in the pan-cancer dataset (Table 1; mean expression values of 3.89 and 8.43, respectively), cell lines from the following cancer categories had elevated expression values of both APOBEC3A and APOBEC3B: bladder (mean values of 4.11 and 9.59, respectively), head and neck (HNSC; 4.93 and 9.54), chronic myelogenous leukemia (LCML; 6.20 and 12.56), and multiple myeloma (MM; 4.12 and 9.52). This evidence concerns the gene APOBEC3B and cancer.