Further analysis of the correlation between mRNA expression levels of these genes and prognosis revealed that 14 of them, including VIM, EPHX3, ACVR1, ANGPT1, TPM3, ALOX15, DIO1, KCNJ2, RSPH9, SOSTDC1, SYCP2, MACF1, TDRD5 and CELSR3, were significantly related to breast cancer prognosis (Table 1). This evidence concerns the gene TDRD5 and breast cancer.