CASP1 and breast cancer: To further examine the degree of apoptosis for sinularin-treated breast cancer (SKBR3) (top side) and normal breast (M10) (bottom side) cells, the flow cytometry-based pancaspase patterns for generic activity of caspases 1, 3, 4, 5, 6, 7, 8, and 9 [22]) are provided (Figure 4A).