TGFB1 and glioblastoma: As depicted in the Figure 4C,D, relapse occurred at a median time of 12.8 months (95%, CI: 7.2–18.3) in low-TGF-β1 expressing GBM, whereas in high and moderate TGF-β1 expressing tumors, recurrence was observed nearly three times earlier (PFS = 4.4 months (95%, CI: 3.5–5.4)).