Karaaslan et al. demonstrated that one polymorphism on the SCCA1 gene, GAGG/AGCTT (rs116864116), was associated with eosinophil count, skin test positivity, and IgE, but not with asthma incidence, and that the variant type had higher binding activities with GATA2 and GATA3 stimulated by IL-4 and IL-13 [36]. The gene discussed is IGHE; the disease is asthma.