It is of note that although three cut-off levels for TARC are used, depending on age [80], only one cut-off value for SCCA2 irrespective of age, 1.6 ng/mL, provided an acceptable result in that it was highly correlated with the diagnosis of AD (79.5% of sensitivity and 95% of specificity across all ages). Here, SERPINB4 is linked to Alzheimer disease.