The protective activities of both SCCA1 and SCCA2 against apoptosis were also observed in irradiated tumor cells, in which inactivation of p38 MAPK followed by inhibition of caspase-3 and -9 was involved, although overexpression of SCCA1/2 in tumor cells did not change the proliferation [6]. Here, SERPINB3 is linked to neoplasm.