CDKN2A and urothelial carcinoma: Although there was no significant difference (P = .332) in p16INK4a expression (high-expression and low-expression) between the 3 different P16 gene group in urothelial carcinoma (Table 1), there were more samples in loss of p16INK4a expression from loss of P16 gene loss group and p16INK4a overexpression from P16 amplification group.