Pantothenate kinase-associated neurodegeneration (PKAN) represents an autosomal recessive hereditary disease in which iron accumulates in the basal ganglia, leading to progressive dystonia, spasticity, parkinsonism, neuropsychiatric abnormalities, and optic atrophy or retinal degeneration.[1] However, the condition remains one of the principal neurodegenerative diseases manifested by brain iron accumulation. This evidence concerns the gene PANK1 and pantothenate kinase-associated neurodegeneration.