INS and Insulin resistance: Other studies demonstrated that 500 mg resveratrol together with lifestyle changes for 12 weeks in a double-blinded placebo-controlled clinical trial in patients with NAFLD (n = 50) did not have beneficial effects on anthropometric measurements, insulin resistance markers such as glucose and insulin levels, Homeostasis Model Assessment (HOMA-IR), and Homeostasis Model Assessment of β- cell function (HOMA-β).