WNK2 and cancer: For KEGG pathway analysis, the candidate targets' genes were primarily located in transcriptional misregulation in cancer, glutamatergic synapse, TNF signaling pathway, MAPK signaling pathway (MAPK, mitogen-activated protein kinase), and so on, indicating that the DE miRNAs and their target genes are related to cancer, neuronal information transmission, gene expression regulation, cell apoptosis, and synaptic transmission (Figure 4(b)).