Titers for most liver autoantibodies seem to correlate with age: in children, lower titers (1:20 for ANA and anti-SMA and 1:10 for anti-LKM-1) can be diagnostic for AIH, whereas in adults, higher titers of ANA (1:80–1:160) can also be found in healthy individuals (9, 21). This evidence concerns the gene SMN1 and autoimmune hepatitis.