A lot of evidence indicates that salidroside inhibits neurocyte apoptosis to protect against Parkinson’s disease, and that it reduces brain cell apoptosis to improve long-term behavioral and histological outcomes that are realized by suppression of phosphorylation of PI3K, Akt, and mTOR (Chen et al., 2012; Fan et al., 2016; Zhang et al., 2016). This evidence concerns the gene AKT1 and Parkinson disease.