NGF therapies have been helpful in protecting the retina and optic nerve in raised intraocular pressure (IOP) models or in neurodegenerative disorders such as Alzheimer’s disease (AD; Lambiase et al., 2009; Roberti et al., 2014) which shares various similarities in ocular manifestations to glaucoma disease (Mirzaei et al., 2017). Here, NGF is linked to Alzheimer disease.