We also evaluated expression levels in PSP, FTD, and PD brains of the four genes that showed strong physical interactions with CXCR4 in our network analyses (CXCL12, TLR2, RALB and CCR5; weighted connection with CXCR4 > 0.25, see above). The gene discussed is CXCR4; the disease is frontotemporal dementia.