CXCL8 and metastatic malignant neoplasm in the lymph nodes: By exploring the relationship between clinic-pathological parameters (age, sex, TNM stage, grade, lymph node metastasis, and tumor size) and CXCL8 expression, we found that the level of CXCL8 was relevant to tumor stage (Pearson chi-square test, p = 0.024) and lymph node metastasis (Pearson chi-square test, p = 0.004), nevertheless other parameters showed no statistical significance with CXCL8 (Table 3).