However, our RNA-seq analysis (Table S1) showed no significant change in the expression levels of LYZ (Ensembl ID: ENSCAFG00000000426), SERPINA1 (Ensembl ID: ENSCAFG00000017646), or VIM (Ensembl ID: ENSCAFG00000004529) in any regressing CTVTs, hence it is unlikely that such markers are specific for the tumor, although we note that histamine biogenesis was a prominent canonical pathway (Figure 6D). This evidence concerns the gene VIM and neoplasm.