They foundfive novel mutations of which most (28.6% of patients)occurred in BBS2 with others occurring in BBS4, BBS7 and BBS12. This finding was in contrast to that reportedin European and North American populations whereBBS1 and BBS10 were the most frequently mutatedgenes accounting for 23% and 20% of BBS patientsrespectively. The gene discussed is BBS10; the disease is Bardet-Biedl syndrome.