Thus, to determine whether ADAM17 deficiency also causes dermatitis in Rhbdf2cub/cub mice, we examined the skin phenotype of Rhbdf2cub/cubADAM17flox/floxK14‐Cre mice in comparison with that of ADAM17flox/floxK14‐Cre and ADAM17flox/flox control mice. The gene discussed is ADAM17; the disease is skin disorder.