NOS3 and cholangiocarcinoma: Interestingly, a significant increase in cell migration was observed in CCA cells that were treated with 100 ng·mL−1 of rhVEGF‐C when compared with the untreated control cells (P = 0.001) (Fig. 2), whereas migration decreased at 200 ng·mL−1, at which concentration a decrease in the level of p‐eNOS was observed.