ERBB2 and breast cancer: These observations are in line with our results on BC cell lines showing an inverse relationship between FUCA-1 expression and aggressiveness, since claudin low triple-negative (MDA-MB231) and HER2 overexpressing (SKBR3) BC cell lines showed lower expression of FUCA-1 in comparison to luminal A ones (MCF-7 and T47D) and luminal B (BT474) both by WB and qPCR.