EP300 and nonpapillary renal cell carcinoma: Particularly, p300 increased the risk of high-grade ccRCC by 7.6% per unit (OR 1.076, IC 1.029–1.236, p = 0.001) and H3AcK14 reduced the risk of high-grade ccRCC by 3% per unit (OR 0.971, IC 0.943–0.999, p = 0.0041).