Increased expression of ALB and decreased expression of LOC100129193 have previously been implicated in hyperhomocysteinemia [14]; however, in both salt-loaded WKY and SHRSP this study saw an increase in LOC100129193 and a decrease in ALB. This disagreement suggests salt-loading may influence inflammatory pathways over different time periods or durations of exposure or that they may not act via homocysteine. This evidence concerns the gene ALB and hyperhomocysteinemia.