Wong et al. found that the expression of protein Cx37-pro319 (encoded by allele C) was less adherent than the expressed protein Cx37-ser319 (encoded by allele T) in mononuclear cell lines, suggesting that Connexin37 may inhibit mononuclear cells adhesion, the initiating factor of arteriosclerosis, to reduce atherosclerosis [16]. This evidence concerns the gene GJA4 and arteriosclerosis.