MTHFR and Stroke: Coagulation/fibrinolytic system-related genes, lipoprotein gene, renin-angiotensin system (ACE) related gene, endothelial nitric oxide synthase (NO), methylenetetrahydrofolate reductase (MTHFR), brain natriuretic peptide (BNP), protein kinase C (PKC), PDE4D, and ALOX5AP have been found to be associated with stroke susceptibility [2, 7].