Therefore, these tumors of our 7a10d subgroup might rather be classified as astrocytoma IDH-wildtype or IDH-mutant (if histological and molecular data are conclusive) or even as oligodendroglioma, NOS (if histological and molecular data are inconclusive) according to the WHO 2016 brain tumor classification system. This evidence concerns the gene IDH2 and astrocytoma (excluding glioblastoma).