In addition, the localization of GLUT1 among thyroid cancers shows distinct patterns: (a) a circumferential plasma membrane focally present within the tumor in papillary carcinomas, (b) asymmetric distribution in the basilar membrane of tumor cells adjacent to the stroma and capillary blood supply, or (c) focally in the center of a tumor in metastatic or anaplastic carcinomas. This evidence concerns the gene SLC2A1 and thyroid cancer.