LncRNA Malat1, one of the down-regulated lncRNAs following propofol sedation, was a highly conserved lncRNA that has been found in various cancers, such as non-small cell lung cancer (Ji et al., 2003) and breast cancer (Feng et al., 2016), and plays a role in the proliferation of myocardial cells (Zhao et al., 2015). This evidence concerns the gene MALAT1 and cancer.