To get an insight into how ∆Np73 may enhance HIF-1α stability we generated a ranked gene list using our previous analysis of differentially expressed genes between breast cancer patients with high vs. low ΔNp73 levels (Dataset 1) [21], and investigated which biological pathways ∆Np73 alter using the Broad Institute Gene Set Enrichment Analysis tool [28, 29]. This evidence concerns the gene HIF1A and breast cancer.