Based on published data and data from International Collaborative Gaucher Group (ICGG) Registry of 887 nonneuronopathic GD children from birth to younger than 18 years, a proposed algorithm for early diagnosis of GD in pediatric patients was also drafted by Maja et al. [15] in 2014, in which five indicators including skeletal erlenmeyer flask deformity, growth retardation, strabismus and/or oculomotor palsy, serum ferritin levels and tartrate resistant acid phosphatase levels were recommended to be assessed. The gene discussed is ACP5; the disease is Strabismus.