In CF, higher pH was positively correlated with all measured cytokines: IFN-γ (r = 0.414, p = 0.003); IL-10 (r = 0.387, p = 0.005); IL-12 (r = 0.360, p −0.009); IL-13 (r = 0.308, p = 0.028); IL-1β (r = 0.360, p = 0.009); IL-2 (r = 0.367, p = 0.008); IL-4 (r = 0.368, p = 0.008); IL-6 (r = 0.334, p = 0.017); IL-8 (r = 0.359, p = 0.013) and TNF-α (r = 0.329, p = 0.022). The gene discussed is TNF; the disease is cystic fibrosis.