Most common grade 3/4 trabectedin-related AEs were leukopenia (n = 14, 18.2% of patients), neutropenia (n = 12, 15.6%), thrombocytopenia (n = 7, 9.1%), alanine aminotransferase (ALT; n = 6, 7.8%) increase, aspartate aminotransferase (AST; n = 5, 6.5%) increase, and nausea/vomiting (n = 4, 5.2% each) (Table 4). Here, GPT is linked to Decreased total leukocyte count.