Similar findings were obtained in mouse neuroblastoma cells and in primary culture of mouse MSNs, where lentiviral expression of Htt138Q-1exon results in enhanced SOCE through the involvement of the sensor STIM1 and of both TRPC1- and Orai1 subunits forming a heteromeric channel (Vigont et al., 2015). This evidence concerns the gene STIM1 and neuroblastoma.