AGT and aneurysm: Angiotensin-II can be used as the hypertensive agent (Nuki et al., 2009; Kanematsu et al., 2011; Pena Silva et al., 2014; Chu et al., 2015b), supported by data demonstrating that angiotensin-converting enzyme inhibitors can attenuate aneurysm rupture (Li et al., 2014).