Some AFs were significantly higher in ER/PR positive lesions than ER/PR negative lesions [ER(+) vs. ER(−): AFsd 13.02 ± 20.28 vs. 7.33 ± 10.96 kPa2/10, P = 0.019; AFmean 29.22 ± 53.32 vs. 14.36 ± 26.72 kPa2/10, P = 0.016; PR(+) vs. PR(−): AFsd 13.59 ± 20.85 vs. 7.28 ± 11.05 kPa2/10, P = 0.01], without significant correlation with HER2, Ki-67 expression and lymph node metastasis. This evidence concerns the gene MKI67 and metastatic malignant neoplasm in the lymph nodes.