CASP8 and infection: For example, Ghrici M. et al. showed activation of caspase-8 already in 2 hours after infection of MCF7 cells with strain AF2240, in contrast to the data presented by Elankumaran S. et al. [43] and Ravindra P. [44], where activation of caspase-8 was demonstrated only after 48 and 24 hours, respectively.