Similarly, mutations in SLC39A4 (ZIP4) and SLC39A13 (ZIP13) have been linked to Zn deficiency and/or accumulation in specific cellular compartments resulting in acrodermatitis enteropathica and spondylocheiro dysplastic Ehlers-Danlos syndrome, respectively [20–23]. Here, SLC39A4 is linked to acrodermatitis enteropathica.