In 2011, Bertrand and colleagues created the Lmna ΔK32 knock-in mouse; this strain harbors a severe congenital muscular dystrophy (L-CMD) mutation [86] that leads to the loss of lysine 32 in the N-terminal domain of LMNA (Table 1). Here, LMNA is linked to congenital muscular dystrophy due to LMNA mutation.