LMNA and Emery-Dreifuss muscular dystrophy: In general, the early prenatal onset is associated with lethal fetal akinesia, late prenatal onset with severe lamin-related congenital muscular dystrophy (L-CMD), onset before 1 year with dropped head L-CMD, onset in childhood or young adulthood with classic EDMD, later onset with LGMD1B, and finally, the end of the spectrum where no skeletal muscle involvement is noted [68,69].