CD4 and autoimmune hepatitis: Thus, it is likely that the EM component of Tregs is reflective of extensive efforts to suppress antigen‐primed effector T cells in the liver.40 Future studies into the T‐cell receptor repertoire of both CD4 and Tregs in treatment‐naive AIH would be of interest to determine whether these cells are clonally expanded subsets that respond to the same antigen.