INS and diabetes mellitus: The following electronic databases were searched: PubMed and MEDLINE (using the Ovid platform), Scopus, BIOSIS, Embase, ClinicalTrials.gov, Google Scholar, and Springer Online Archives Collection, from January 1966 to July 2017, using the terms “insulin,” “glargine,” “glargine 300,” “glargine 100,” and “basal insulin” in combination with the term “diabetes.” Articles resulting from these searches and relevant references cited in those articles were examined.