On the other hand, in T1DM patients, the comparison between both insulins showed the noninferiority of Det versus Glar-100 to reach the HbA1c < 7% goal, as well as the FPG values or the proportion of individuals achieving the HbA1c < 7% goal in the absence of confirmed hypoglycemia, although self-measured FPG levels were significantly lower with Glar-100 than with Det. This evidence concerns the gene INS and Hypoglycemia.