Patients with complete C2 deficiency had significantly lower C2 concentration than both patients with partial C2 deficiency with infections (p = 0.01) and subjects with partial C2 deficiency without infections (p = 0002); however, the difference in C2 concentration between patients with partial C2 deficiency with infections and subjects with partial C2 deficiency without infections was not significant (p = 0.67) (Figure 4C). The gene discussed is C2; the disease is infection.