Indeed, it was reported in the literature that demyelinating disease in SLE in particular has the propensity to be accidentally misdiagnosed as other CNS affecting diseases such as MS39, and a case report showed an induction of SLE by interferon beta-1 treatment of a MS patient40, thereby demonstrating the potential autoimmune-link between these two diseases. This evidence concerns the gene IFNB1 and systemic lupus erythematosus.