For example, in a patient with a TiME-I tumor (MPM.003; HLA-A*01:01, HLA-A*30:02, and HLA-B*18:01), the BAP1N645K neoantigen (LKCVEAEIAKY) (derived from the most common gene mutation in MPM; ref. 33) was present in high abundance, and its corresponding MHC-I proteins were also present at high levels. This evidence concerns the gene HLA-A and neoplasm.